@eperlste - Twitter Profile Analysis

Analysis of 200 tweets by Ethan Perlstein, from 01 Jan 2022 to 18 Jan 2022.

@eperlste twitter profile photo

Ethan Perlstein


Cure sherpa, biotech builder, solo VC, evolutionary pharmacologist, mTOR worshipper, CEO @PerlaraPBC (YCW16), CEO @epalrestat, cofounder of Kai & Luca

55,803 tweets
88,917 favourites
12 tweets per day
2011 since
1,867 following
514 listed
Oakland, CA location

Top Tweets by @eperlste

Ethan Perlstein
Biotech builders/solo VCs unite! https://t.co/ey0iNV63UU
18 Jan, 2022 - 04:29 PM UTC
Ethan Perlstein
Fascinating to watch how the new YC Standard Deal flips the script: Companies used to be stealth throughout the batch to avoid distractions of fundraising or because YC partners told them to stay mum. Now the advantage goes to announcing you’re in the batch as soon as possible!
18 Jan, 2022 - 04:01 PM UTC
Ethan Perlstein
Inescapable law of biotech platforms: as therapeutic ambition goes to infinity, clinical development bandwidth goes to zero. Ultrarare diseases — 10 < N < 1,000 worldwide, or most rare diseases — are economic nonstarters for companies. How do we fix this? (I have an idea..)
17 Jan, 2022 - 08:37 PM UTC
Ethan Perlstein
Need to add “secular genotyping Jew” to my profile..
15 Jan, 2022 - 05:49 PM UTC
Ethan Perlstein
Been waiting a few years to be able to say this: Perlara is growing! https://t.co/nm5UmwVZwF
14 Jan, 2022 - 10:48 PM UTC
Ethan Perlstein
New YC Bio Founder Hour tomorrow at an earlier 9AM PT start time with the founders of @LiyfeClinic — join us! https://t.co/TquKFy4wEP
14 Jan, 2022 - 09:29 PM UTC
Ethan Perlstein
I wish America were capable of this kind of collective action and scientific determinism. Liberals, conservatives, doesn’t matter. We’re united in our impulses toward instant gratification, liberty and minimization of risk. It’s actually the quintessentially American response https://t.co/jxvsd624kt
14 Jan, 2022 - 04:15 AM UTC
Ethan Perlstein
You don’t have to be an Open Access/Open Science maximalist like @mbeisen (or me!) to agree that the current system has been collapsing on itself over the last 20 years. I ask those who hold power in academia — what are doing right now to reform/fix it?
13 Jan, 2022 - 11:50 PM UTC
Ethan Perlstein
Grateful for @AngelList back office and all my LPs for their capital, which have enabled me to become a biotech operator and solo VC over the last few years. With a $2M fund I’ll write fewer but larger checks ($250K). Can’t wait to meet the @ycombinator W22 biotech batch!
13 Jan, 2022 - 11:33 PM UTC
Ethan Perlstein
If the powers that be in biology keep blocking it from following physics and math down the preprint path, a generation of young scientists will en masse quit academia. And they’d be perfectly justified. All in the name of preserving impact, status and power. What a shame. https://t.co/Z9Kctw2Zsc
13 Jan, 2022 - 07:46 PM UTC
Ethan Perlstein
Join us for Gene Fixers TODAY with guests @AndrewWLo, Yutong Sun, and Anthony Philippakis https://t.co/ix2nYZP1Ea
13 Jan, 2022 - 07:15 PM UTC
Ethan Perlstein
As a country/culture obsessed with test prep, how did we fail so hard on COVID?
12 Jan, 2022 - 10:32 PM UTC
Ethan Perlstein
Academics after joining a crypto-funded research institute https://t.co/RuXnUxZ3XX
12 Jan, 2022 - 07:48 PM UTC
Ethan Perlstein
SFO✈️DEN✈️MSP🚗RST🏥Mayo Clinic
12 Jan, 2022 - 06:31 PM UTC

Top Retweets by @eperlste

Brian Chesky
1. Starting today, I'm living on Airbnb. I’ll be staying in a different town or city every couple weeks
18 Jan, 2022 - 04:19 PM UTC
jeff carroll
Very exciting update from @Roche and @ionispharma about their Huntingtin-lowering drug, tominersen. A new phase II study in earlier stage HD is apparently being planned... https://t.co/hDCedHcATJ
18 Jan, 2022 - 02:27 PM UTC
Aarika Rhodes for CA-32🍎🦉
I was interviewed by @politico on how #Bitcoin is impacting the 2022 midterms. There’s a new wave of representation like myself that sees where the opportunities are for the people of this country. And they’re trying to unseat incumbents like Rep. Sherman https://t.co/ZzAyBvBqny
17 Jan, 2022 - 02:12 AM UTC
How scientists have directly observed bacteria use their surface appendages called competence pili to "harpoon" DNA in the environment to speed up their evolution [source, read more: https://t.co/yyoHnaNPQW]
15 Jan, 2022 - 12:10 PM UTC
Seán Doran
Hunga #Tonga-Hunga Ha'apai #eruption at 04:00 UTC on Jan 15. images courtesy #Himawari8
15 Jan, 2022 - 06:13 AM UTC
Sam Finlayson
Have biotech skills, some scheduling flexibility, and a desire to help rare disease patients? I strongly recommend checking out Perlara. Part-time by default, so you can do it in addition to your "day job" whether you are an academic or an industry person. Great mission + culture https://t.co/97mBDG1bUC
15 Jan, 2022 - 03:45 AM UTC
Dr Bethany Halford
The medchem campaign behind @pfizer's oral antiviral Paxlovid. Thanks to Dafydd Owen for talking to me about this work: https://t.co/AX8AO8YF7j
14 Jan, 2022 - 06:10 PM UTC
Brian Wallach
I cried multiple times as I read @samstein’s truly beautiful article about me. I have been very public about my fight but for the first time I felt naked before the world. I used to fear this moment, but the poetry of Sam’s words made me thankful for it. https://t.co/1RhXAyUVyC
14 Jan, 2022 - 03:45 PM UTC
Jean C9orf72
Any one who does not understand the urgency of treating devastating neurological conditions during the long prodromal period rather then when the body or mind has been defeated enough to demonstrate clinical symptoms should read Seth’s blog ! https://t.co/IUpWIHJPVa
14 Jan, 2022 - 12:36 AM UTC
Matt Kaeberlein
IMO, here's an example of high quality media coverage of the longevity space. Need more of this. The Fountain of Youth has long been a dream. Some scientists are testing the waters with drugs that one day could make a dent in our aging process. https://t.co/Bn9ma88jqk via @WSJ
13 Jan, 2022 - 03:33 PM UTC
euan ashley
Excited to share some new work from us today on ultra-rapid genome sequencing for the diagnosis of critically ill children and adults. In critical care settings, genetic diagnosis can shorten stays, direct precision therapy, save money, and help with family planning. 1/
12 Jan, 2022 - 11:02 PM UTC
Ethan Perlstein
🧬 Gene Fixers 🛠 January theme: Business of Rare This week’s guests: @AndrewWLo, Yutong Sun (https://t.co/hU5xCcRwPY), Anthony Philippakis (@GVteam) Tomorrow, Jan 13 @ 12PM PT/3PM ET in @clubhouse. Join us! https://t.co/ix2nZ06CvI
12 Jan, 2022 - 04:42 PM UTC
Benjamin de Bivort
Hi friends - Delighted to share a recent preprint on the mechanistic origins of individual behavior, the culmination of a major project led by @MAChurgin and @dolavrent supported by @Matt_AYSmith @Ruixuan3 @eboyden3 https://t.co/yRPXTdRVGY
11 Jan, 2022 - 11:18 PM UTC
Jake Tapper
A lovely profile of the great ⁦@bsw5020https://t.co/KlOWAmwpnI
11 Jan, 2022 - 02:55 PM UTC
Brian Wallach
Thank you ⁦@levfacher⁩ and ⁦@statnews⁩ for telling our story in this raw, poignant and beautiful piece. And yes, I am going to prove you wrong with the help of tens of thousands of friends at ⁦@iamalsorg⁩. #NeverGiveUp https://t.co/xEoieQ9ocY
11 Jan, 2022 - 02:38 PM UTC



33 tweets
126 replies

Twitter Client

187 Twitter for iPhone
13 Twitter Web App

Tweet Times


Tweet Days



5 - eperlste
2 - mwseibel
2 - bsw5020
2 - bchesky
1 - OdedRechavi
1 - PrakashLab
1 - celinehalioua
1 - PerlaraPBC
1 - PeterHotez


11 - eperlste
5 - ClementYChow
3 - atgmeup
3 - bradloncar
3 - WillManidis
3 - PracheeAC
3 - bijans
3 - jamessinka
2 - kamens


3 - #JPM22


4 - @Clubhouse
3 - @ycombinator
2 - @AndrewWLo
1 - @PerlaraPBC
1 - @stopbatten
1 - @BiotechCH
1 - @cngarabedian
1 - @dnatieclub
1 - @GVteam