NEJM's Twitter Profile Analysis @nejm on Twitter

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Corey S. Davis, J.D., M.S.P.H. discusses the recent federal settlement with Purdue Pharma over its actions to increase prescriptions of its opioid medications.

Covid-19 Rx: Your task is to gather data, develop a differential diagnosis, order additional diagnostic tests, and treat the patient. (Optimized for desktop PCs and most tablets.) @NEJMGroup #COVID19

An 83-year-old man presented with fatigue, weight loss, and postural hypotension. Computed tomography of the abdomen revealed marked enlargement of both adrenal glands, and a diagnosis of primary adrenal lymphoma was made.

Over the objections of numerous members of Congress, state attorneys general, and families of people killed by opioids, Purdue Pharma and the Sacklers were permitted to enter into plea agreements that resolve all current federal criminal and civil charges against them.

Now available, the Covid-19 Vaccine Resource Center includes important articles, related resources, and answers to FAQs to provide practical guidance for your practice and patients. #COVID19 #IDTwitter

Ewing’s sarcoma, an aggressive cancer of bone and soft tissue, primarily affects children and young adults. A t(11;22) translocation is noted in 85 to 90% of cases. Management includes surgery, radiotherapy, and chemotherapy. The 5-year survival is about 70%.

The NEJM Race and Medicine topic page features a selection of NEJM articles on race and medicine with implications for improving patient care, professional training, research, and public health. All articles assembled on the page are freely available.

Free Access: NEJM Covid-19 Articles and Resources. #COVID19 #SARSCoV2

Recent analyses provide reassurance about using paclitaxel-coated devices in patients with peripheral arterial disease, but the FDA believes that clinical studies of these devices should continue and should collect long-term mortality data.

In this audio interview conducted on January 13, 2021, the editors are joined by South African infectious disease physician Salim Abdool Karim to discuss Covid-19 in Africa and the impact of a newly discovered SARS-CoV-2 variant. #COVID19 #IDTwitter

A federal “Transparency in Coverage” rule requires insurers to disclose list prices and historical net prices for medications and to give patients personalized cost-sharing estimates. Despite industry opposition, the rule may endure under the Biden administration.

Remarkable progress in drug development has transformed pulmonary arterial hypertension from a disease that is rapidly fatal into one that in some patients may be managed with pharmacotherapy.

Patients with pulmonary hypertension due to interstitial lung disease were randomly assigned to inhale treprostinil or placebo. At 16 weeks, there was a significant improvement in exercise capacity with inhaled treprostinil as compared with placebo, assessed by a 6-minute walk.

Randomized convalescent plasma trials of hospitalized #COVID19 patients provided weak evidence of clinical efficacy. No unexpected safety signals beyond the recognized risks of plasma transfusion have emerged, nor has there been evidence of antibody-dependent enhancement.

Among 3,000 hospitalized patients with #COVID19, recipients of high-titer convalescent plasma had a lower mortality at 30 days than recipients of low-titer plasma. The effect of high-titer plasma was greatest in the subgroup of patients who were not on mechanical ventilation.

A 73-year-old woman who is hospitalized for cellulitis responds rapidly to treatment with vancomycin and ceftriaxone and is discharged. Five days after discharge, her platelet count, which was normal on admission, is found to have dropped to… #MedEd https://t.co/40emToISRS https://t.co/xGHDQqvOIB

The CDC on Sunday officially recommended use of Moderna's #COVID19 mRNA #vaccine in adults aged 18 and older. The agency notes that "preliminary data suggest that the Moderna COVID-19 vaccine might ... provide some protection against asymptomatic infection."

The CDC now recommends treating uncomplicated gonorrhea with a single 500-mg intramuscular dose of ceftriaxone, according to updated guidelines in MMWR. #STI

Our discussion "Negotiating Your First Contract," closes tomorrow, December 18. #MedStudentTwitter #MedTwitter

Among U.S. adults aged 25 to 44, there were 19% more deaths than expected — or 12,000 people — from March through July 2020. #COVID19

The efficacy of Moderna's mRNA #vaccine against #COVID19 — and severe illness in particular — was confirmed on Tuesday in data released by the FDA in advance of its vaccine advisory committee meeting this Thursday.

What’s the most appropriate additional test for an asymptomatic 65yo white man who has mild elevations in serum aminotransferases, lipids, and fasting glucose; a normal level of alkaline phosphatase; no history of alcohol use disorder… #MedEd https://t.co/6sPQPWP5mH https://t.co/9ouqFSm6Eq

ICYMI: 3 local experts, from Boston based schools and hospitals, sat on the advisory committee to the FDA that recommended the Pfizer COVID-19 vaccine for approval. https://t.co/XMRAQrTAEk

An FDA advisory committee voted on Thursday that the potential benefits of the Pfizer and BioNTech #COVID19 #vaccine outweigh its risks for people ages 16 years and up.

Celebrating our anniversary today! 🎉 One year ago, we launched NEJM Catalyst Innovations in Care Delivery. NEJM Catalyst itself turns five. Please enjoy some virtual cake, on us. 🍰

Three U.S. medical societies issue an update on joint recommendations for the prevention, diagnosis, and treatment of #LymeDisease. https://t.co/NPbs12qMG3 https://t.co/fnaPFNBdfg

#ASH2020: A preliminary study shows that patients on chronic anticoagulant or antiplatelet drugs for other conditions do not fare better than other patients after receiving a diagnosis of #COVID19. Dr. Gwendolyn Ho chats with @NEJMGroup’s Joe Elia. https://t.co/ym6lKgChbz https://t.co/dj3BCBOpz8

Pfizer and BioNTech's mRNA #vaccine against #SARSCoV2 seems to start working soon after the first dose. Meanwhile, the AstraZeneca vaccine showed 62% efficacy among people who received two full doses and 90% efficacy among those who received a half-dose followed by a full dose.

A preliminary study in California shows that patients on chronic anticoagulant or antiplatelet drugs for other conditions don't fare any better than other patients after receiving a diagnosis of #COVID19. Dr. Gwendolyn Ho chats with Joe Elia. https://t.co/DkOtnLbt5I #ASH20 https://t.co/qtkbkFxtUn

.@PaulSaxMD offers some tips for getting through the next few months safely -- and with some joy -- while we await widespread vaccination against #COVID19. https://t.co/Q80FbXiFDw