@nejm - Twitter Profile Analysis

Can we take advantage of the renewed attention to nursing homes the tragedy of Covid-19 brought to design better long-term care in the U.S.? Watch this Perspective Roundtable, where experts assess the most pressing gaps and challenges. https://t.co/BloDbmtPFy

Medicine promotes an inconsistent message on SIDS: authoritative statements imply that SIDS is a consequence of unsafe sleep, but there is vague acknowledgment that biologic factors are involved in these deaths. https://t.co/Q0EstpKJGa

A new bill, the Dietary Supplement Listing Act of 2022, would create the impression of reform inthe supplement industry while leaving the current lax regulatory framework largely untouched. https://t.co/7NVN4PwfVO

This case report describes a patient in Sweden who had an out-of-hospital cardiac arrest and received defibrillation with an automated external defibrillator delivered by a drone (shown in a video). https://t.co/PvjYPJmO90

A recent study of mouse models implicates dopaminergic nerve terminals in the amygdala in releasing the brakes on REM sleep and on cataplexy in a mouse model of narcolepsy. https://t.co/QsjovgyRvs

A 61-year-old man presented with a 2-day history of left upper back pain. CT angiography revealed aneurysmal dilatation of the ascending aorta, aortic arch, and descending thoracic aorta. https://t.co/fE5ZmL79vp

A 40-year-old man presented to the dermatology clinic with a 2-week history of a scaly foot rash, joint swelling, and low back pain. What is the diagnosis? https://t.co/kQrNuVmVXg

The duration of protection from the BNT162b2 Covid-19 vaccine among children and adolescents is uncertain, particularly amid circulation of the omicron variant. New research findings are summarized in a short video. https://t.co/N0mzBWd225

Richard Pierson III, M.D., discusses the implications of recent efforts to transplant pig organs into humans. https://t.co/OOllHMadQG

Following widespread falsehoods about Covid-19 and its treatment and prevention, the ABIM has informed doctors that disseminating misinformation is grounds for disciplinary sanctions. https://t.co/xT42BycHi0

In light of the recent clinical cases of pig-to-human kidney and heart transplantation, taking stock of progress in xenotransplantation can help us set realistic expectations for clinical adoption. https://t.co/a5u39wulSP

With the emergence of the omicron variant of SARS-CoV-2 in November 2021, these investigators found how rapidly it had spread across Canada among both vaccinated and unvaccinated persons. https://t.co/kDMsCZ7EoZ

A 73-year-old man presented with fatigue and diffuse bone pain. Workup showed pancytopenia, long-bone osteonecrosis, and Gaucher’s cells on bone marrow biopsy. https://t.co/DruAwXTbFJ

A 57-year-old man with polyarteritis nodosa was evaluated for cough and pulmonary opacities. Chest CT revealed multifocal clustered centrilobular nodules and opacities in a tree-in-bud pattern. Read this case record of the MGH. https://t.co/RMKFNaa1tf

New review article highlights recent changes in the classification and management of brain tumors in children. https://t.co/8kV3t2SLAU

The sixth issue of NEJM Evidence is now available! Read more: https://t.co/87v23nCNNR #MedTwitter #ClinicalTrials #EBM https://t.co/gvSSOonZno

“#ECigarette Use, Small Airway Fibrosis, and Constrictive Bronchiolitis,” an Original Article by @LidaHariri et al. is now available. https://t.co/I6zoLfemXe #PulmTwitter #MedTwitter @MGH_PCCM @MGHPathology @MGHMedicine @MassGeneralNews @harvardmed @DukeHealth @dukemedicine https://t.co/OfcbdjROik

“Harm-to-Benefit of Three Decades of #ProstateCancer Screening in Black Men,” an Original Article by @SBasourakos et al. https://t.co/o9SYjRM0KP #PCSM #UroSoMe @WCMUrology @jeshoag @CaseUrology @nyphospital @Chris_Barbieri1 @jimhumd @fredhutch @UMichUrology @DrSpratticus https://t.co/j15Z2CwkbX

In this series, @LidaHariri et al. associate the histopathologic pattern of small airway-centered fibrosis, including constrictive bronchiolitis, with vaping; potentially defining a clinical and pathologic entity associated with #ecigarette use. https://t.co/I6zoLfemXe https://t.co/T8wt1QC5Uh

Given persistent disparities in outcomes for Black men with #ProstateCancer, Spyridon P. Basourakos, MD, et al. re-examine the harms and benefits of PSA screening. https://t.co/o9SYjRM0KP #AUA22 #PCSM @AmerUrological https://t.co/EgjVFTYQJq

Four pts who developed shortness of breath, chest pain, and mild progressive airway obstruction with #ecigarette use had lung biopsies. Small airway-centered fibrosis, including constrictive bronchiolitis and MUC5AC overexpression, was seen in all pts. https://t.co/I6zoLfemXe https://t.co/7cvulVZCow

In this editorial, William G. Wierda, MD, PhD, discusses the recently published phase 3 GLOW trial, addressing adverse events, needed follow-up, and its implications for optimizing future trials. https://t.co/lRXk8EM7TL #LeuSM #CLL #MedTwitter @MDAndersonNews https://t.co/2wXDVeqYIQ

In older patients and/or those with comorbidities with untreated #CLL, treatment with ibrutinib-venetoclax was superior to chlorambucil-obinutuzumab, with fewer events and longer PFS after just over 2 yrs of follow-up. Read about the GLOW trial: https://t.co/gYjksIhp96 #LeuSM https://t.co/aBnpdeKhFO

“The challenge is how to test it ethically and with our duty to do no harm, dismantling structural racism and historic patterns of inequity that persist today.” An editorial by @AhizechukwuEke and @VBKerry: https://t.co/YeUGaMybeN #GlobalHealth #HPV #gyncsm https://t.co/WGBbZziFEj

"Providers use gestational age to interpret abnormalities of fetal growth, to plan referrals, and to decide if, or when, to intervene for fetal benefit." Read more about the trial by Pokaprakarn et al. using AI to estimate gestational age: https://t.co/Cc3NTTDzfg #AIinMedicine https://t.co/ATW57KWYCt

This review illustrates how DSMBs ensure the safety of patients in a clinical trial. DSMBs may terminate an ongoing trial if there is clear evidence that the experimental treatment is found to be harmful with no offsetting evidence of benefit. https://t.co/VmHrYOuBYS #MedTwitter https://t.co/ipc2HG7Klq

In this Phase 3 trial, Ravulizumab demonstrated rapid and sustained improvements in both patient- and clinician-reported outcomes in adults with anti-AChR antibody-positive gMG, and had a side-effect and adverse event profile that did not limit treatment. https://t.co/9mlCOUtHlh https://t.co/Y64v0nxkxr

Learn to love the Methods section. Request institutional access to NEJM Evidence today: https://t.co/LtwUwT2uFY

Patients with enteric hyperoxaluria received reloxaliase, an enzyme that degrades oxalate in the GI tract, or placebo with food for 4 weeks. There was a greater reduction in urinary oxalate excretion with reloxaliase. https://t.co/x7m12QHyWX #NephTwitter #UroSoMe #ClinicalTrials https://t.co/rzCpd6YfLM

“If the effects of single-dose #HPV vaccination are durable...this approach could serve to close the gap between the @WHO’s goal of 90% HPV vaccination coverage by 2030 and the 15% of girls currently vaccinated globally...” https://t.co/sh4LN3h0jS #GlobalHealth #gyncsm https://t.co/FiZMIgFO6g

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